SUBSCRIBE AND SAVE!   |  SIGN ME UP!

Menu
eye vitamins
Vision supplements, or eye vitamins, are for everyone.

MacuHealth

Written by MacuHealth
Reviewed by Jim Stringham, Ph.D.

Macular carotenoids are powerful and specific antioxidants that our body uses to fight a battle against free radicals in the retina. Since the body doesn’t synthesize these special nutrients – Lutein, Meso-Zeaxanthin and Zeaxanthin – on its own, they must be obtained via dietary consumption of dark leafy greens and other colored fruits and vegetables. 

Often, diet isn’t enough, and low intake of these crucial nutrients can result in damage from oxidative stress and inflammation that can lead to age-related macular degeneration (AMD), the leading cause of vision loss in those over 60 years of age.

The problem is that the average person consumes only one to two milligrams of macular carotenoids daily. But research has proven the body receives significant benefits when taking between 20 to 25 mg daily. Additionally, modern farming conditions have caused the nutritional value of fruits and vegetables to decline.

But scientific evidence overwhelmingly shows that our eyes need Lutein, Meso-Zeaxanthin and Zeaxanthin to experience enhanced visual performance, protect our eyes from blue light and manage AMD risk and symptoms. At what age should we start taking these vital ingredients? We’ll look at when is a good time to start taking eye vitamins.

Why Eye Vitamins Are for Everyone

We’re relying more on our computers, tablets and smartphones. The drawback is that these devices emit shortwave frequencies (i.e., blue light) with high energy that can damage the macula over time. Additionally, there are other unwelcome symptoms that exposure to blue light can cause:

  • Dizziness
  • Headaches
  • Dry eye
  • Sleep disruption
  • Eye strain
  • General visual discomfort

Lutein, Meso-Zeaxanthin and Zeaxanthin benefit eye health and protect the retina from blue light-induced damage by increasing your macular pigment density. In other words, they act as a defensive wall to lower the risk of various eye diseases and undesirable symptoms that can arise due to blue light exposure. When found in an extremely pure and highly bioavailable form, as they are in eye vitamins like MacuHealth, they can also have the following benefits:

  • Enhanced sleep
  • Reduced eye strain
  • Reduced headache frequency
  • Improved visual performance (e.g., contrast sensitivity, glare, speed of processing)
  • Limit the risk of long-term eye health complications

Why Eye Vitamins Are Vital for Older Adults

As we get older, the risk of developing eye disease increases. We need carotenoids to build macular pigment and protect our vision. These diseases include cataracts and AMD. By enriching macular pigment with eye vitamins, you can help manage AMD symptoms and save eyesight in a diseased eye and, in more advanced forms of the disease, possibly delay the onset of the disease in the other eye.

Additionally, when post-cataract patients have had their crystalline lens removed, it takes out the natural blue light filtration normally provided by the lens. The replacement lens is clear. While good in many ways, the new lens allows blue light to pass through to the retina, making it more susceptible to damage. Taking an eye vitamin like MacuHealth can help to guard against this damage by building up the defense provided by macular pigment.

Why Eye Vitamins Are Vital for Athletes

Have you ever tried to catch a fly ball with the bright sun in your eyes? Baseball players need strong contrast sensitivity, your ability to distinguish between an object and its background, to make the big play. And researchers and eye care professionals state that testing for contrast sensitivity is a better measure of your visual performance than the standard examination of reading letters off a chart. Good contrast sensitivity allows you to detect subtle differences in shading and more accurately track objects (e.g., a ball) moving against varying background illumination.

Visual Processing Speed

In almost any sport, there are many instances where faster visual processing speed is a great advantage. For example, it’s hard for players to predict where a rebound will go once it leaves the backboard. Also, hockey goalies must anticipate a puck’s trajectory when an opposing player makes a lightning-fast shot. But if you have high visual processing speed, you can react quicker, better predict where things will be at any given time and make better decisions as you play.

 

Glare Disability and Recovery

Sunlight and bright stadium lights can wipe out your visual field and wear out your eyes. Look at how much a quarterback squints in the fourth quarter – this is a sign that he’s struggling with glare from the sun and stadium lights. Ocular fatigue factors into how well players perform, and glare makes it hard to judge the small but vital details. Several studies have demonstrated that the more you build up your macular pigment level, the greater benefit you’ll experience in terms of glare – both seeing through glare from bright lights and recovering from exposure to bright light.

Eye vitamins such as MacuHealth and MacuHealth Plus+ are specifically formulated with Meso-Zeaxanthin, Lutein and Zeaxanthin to enrich and restore macular pigment to optimum levels with continued use. And they’re safe and recommended for anyone, no matter their age.

Micro-Micelle Technology
How does Micro-Micelle Technology work?

MacuHealth

Written by MacuHealth
Reviewed by Jim Stringham, Ph.D.

A supplement label may promise to include a defined portion of active ingredients, but research shows that the truth could be vastly different. Cheap formulations and storage techniques can degrade nutrients, causing them to lose their bioavailability to light and oxidation, meaning you aren’t getting everything promised on the bottle.

“At present, clinicians and consumers are not adequately informed via product labeling,” stated Dr. David Phelan, Professor John Nolan and Dr. Alfonso Prado-Cabrero in their study on supplements in the journal Nutrients.1 “However, it is also important to point out that there are quality and effective carotenoid products on the market, which have scientific evidence to back up their claims of label and efficacy.”

MacuHealth enhances the stability of its Triple Carotenoid Formula with something called Micro-MicelleTM Technology. It allows the body to absorb nutrients inside the supplement at a significantly higher rate. In a recent clinical study, MacuHealth’s formula provided the highest bioavailability with significantly higher serum and retinal response when compared to a standard macular carotenoid supplement.2

But how does Micro-Micelle Technology work? We’ll explain the process and what it means to MacuHealth users.

Why Micro-Micelle Technology Matters?

As stated above, studies have shown that the active ingredients in most carotenoid supplements that come in the form of a powder or tablet corrode, causing their potency to diminish or disappear altogether.  This means your eyes won’t receive the necessary nutrients to boost your vision, absorb harmful blue light, or manage the symptoms of age-related macular degeneration.

MacuHealth, an oil-based supplement, is formulated to stabilize the powerful carotenoids – Lutein, Meso-Zeaxanthin and Zeaxanthin – in its formula better than other supplements. But these nutrients, which appear in the supplement in their pure, natural form, tended to crystalize in the supplement’s previous version, making the carotenoids difficult for the body to absorb. Researchers started looking for a way to prevent these carotenoids from bonding together so more of them could reach the macula to enhance a patient’s vision.

How Does Micro-Micelle Technology Work?

Lutein, Meso-Zeaxanthin and Zeaxanthin make their way to the macula through a protein in the body called SR-B1. Because these carotenoids were clumping together, SR-B1 wasn’t taking as many of them as it could to the eye. A system needed to be created to keep ingredients stable and from crystallizing.

The answer came in the form of natural, organic acids (acetate). When you add acetate to each end of the carotenoid molecule, they maintain their solubility,3 greatly enhancing bioavailability. Placing these non-crystallized carotenoids in a stabilizing matrix, such as Vitamin E and sunflower oil, prevents oxidation. 

The acetates prevented the carotenoids from crystalizing and provided a more efficient way for the SR-B1 protein to transport them to the macular tissues that need them. The utilization of Micro-Micelle Technology marks an improvement over previous iterations of MacuHealth by increasing the bioavailability of the supplement’s formula without any negative side effects. 4

What Does This Mean for MacuHealth Users?

Micro-Micelle Technology ensures that the nutrients inside MacuHealth retain their all-natural form, and that your eyes and brain receive the carotenoids needed to manage AMD symptoms and improve nearly all aspects of visual performance. In short, you’re getting everything you paid for and the benefits that come with it. “This formulation represents a new standard in nutritional vision science and eye care,” says Professor Nolan.

 

For more information about Micro-Micelle Technology and MacuHealth’s Triple Carotenoid Formula, please visit this page.

References

  1. Phelan D, Prado-Cabrero A, Nolan JM. Stability of Commercially Available Macular Carotenoid Supplements in Oil and Powder Formulations. Nutrients. 2017;9(10): 1133.­­
  2. Green Gomez et al 2020. Doi:10.3390/antiox9080767
  3. Torres-Cardona, MD, Torres-Quiroga, JO. Short-Chain Diesters and Process for Making the Same. U.S. Patent 5959138A, 28 September 1999.
  4. Green-Gomez M, Prado-Cabrero A, Moran R, Power T, Gómez-Mascaraque LG, Stack J, Nolan JM. The Impact of Formulation on Lutein, Zeaxanthin, and meso-Zeaxanthin Bioavailability: A Randomised Double-Blind Placebo-Controlled Study. Antioxidants (Basel). 2020 Aug 18;9(8):767. doi: 10.3390/antiox9080767. PMID: 32824736.
dry eye
Eye drops can provide temporary relief from dry eye.

MacuHealth

Written by MacuHealth
Reviewed by Jim Stringham, Ph.D.

The lights seem a little brighter than usual. You squint for minutes until your focus readjusts, but you can’t shake the feeling that there’s something in your eyes. They feel gritty and rough as you constantly rub them. They feel itchy around your sockets, and your eyeballs are so sore and inflamed that your vision becomes blurred.

The above paragraph describes what it’s like living with dry eye. This frustrating, and many times, chronic condition affects nearly 16 million Americans, particularly older adults. The ocular irritation may be relieved with a bottle of eye drops, but the ingredients in some of these products exacerbate symptoms. What are some ways you can combat dry eye? We’ll share what causes it, who’s at risk and some methods to treat it.

Causes of Dry Eye

Dealing with the symptoms of dry eye is enough to make you cry. But according to the American Optometric Association, the condition is caused by a lack of tears. Moisture spreads across the eye’s surface, lubricating and protecting them from foreign objects and infection. As we age, tear production and drainage through the tear ducts become imbalanced. The glands in and around the eyelids produce fewer tears or make lower-quality droplets that evaporate quickly, causing them to spread unevenly around the eye.

Tear production can decrease for several reasons. In addition to aging, hormonal changes caused by pregnancy and menopause cause more women to experience dry eye symptoms. Inflammation can develop because of other medical conditions, including rheumatoid arthritis, diabetes and thyroid issues. Antihistamines, decongestants, antidepressants and blood pressure medications can also lead to fewer tears.

Environmental conditions have also caused symptoms to rise in younger people. Smoking and dry climates can intensify dry eye symptoms. So can an increase in your screen time. When looking at electronic devices for an extended amount of time, our eyes blink less, which leads to a decrease in tear production.

Treatments

Here are some simple ways to prevent dry eye symptoms:

  • Regularly blink your eyes when staring at electronic devices for an extended amount of time
  • Take a 20-second break from whatever you’re working on every 20 minutes and focus your eyes on an object 20 feet away
  • Keep blowing fans and heaters away from your face
  • Wear sunglasses outdoors to reduce exposure to wind and other weather conditions
  • Drink the recommended 8 to 10 glasses of water daily to keep your body and tear ducts hydrated
  • Use artificial tears and humidifiers to keep eyes moist

How Supplementing with Omega-3s Helps

Inflammation is at the root of dry eye. Unfortunately, there is no cure. But there are a variety of treatments that can manage symptoms. Most people turn to over-the-counter eye drops. However, using them can make symptoms worse. Some prescriptions control some of the underlying causes of dry eye. There are also invasive procedures to help increase tear production or close the ducts to reduce tear loss.

Another way to soothe inflammation is by supplementing with Omega-3s. In addition to improving brain and heart health, an American Academy of Ophthalmology study shows consuming fish oil through seafood or supplements reduces dry eye symptoms. It also significantly lowers the risk of developing other retinal diseases like age-related macular degeneration (AMD).

Yet many people are hesitant to go on a fish oil regimen because of the low-quality ingredients that cause odd-smelling “fishy burps.” The formula for the supplement TG Omega-3 by MacuHealth uses oils from small, traceable open-water fish refined to the highest purity and quality. This ensures optimum health without undesirable fish burps. 

carotenoids
Are you getting enough carotenoids in your diet?

MacuHealth

Written by MacuHealth
Reviewed by Jim Stringham, Ph.D.

You may not know carotenoids, but chances are you’ve heard of antioxidants. They’re robust components of healthy foods that take on molecules known as free radicals, which damage cells inside the body. 

There are over 700 carotenoids found in nature. Most fruits and vegetables contain carotenoids. Also, some leafy greens feature unique carotenoids that fight an intense battle against free radicals inside the retina.

“The retina, especially the macula, is thought to be an environment of high oxidative stress, meaning that there is an abundance of free radicals—molecules that damage proteins and DNA within cells. Antioxidants fight free radicals and are thought to help protect the retina from this damage,” explains Dr. Ivana Kim at Harvard Medical School.

If left unchecked, the damage from oxidative stress can lead to age-related macular degeneration (AMD), the leading cause of vision loss in those over 60. Interestingly, three specific carotenoids deposited in the retina are clinically proven to prevent and manage the symptoms of AMD. We’ll look at how these three carotenoids guard the eyes and can improve eyesight and cognitive health.

Lutein, Zeaxanthin and Meso-Zeaxanthin

As Dr. Kim stated above, the retina needs a lot of oxygen to fuel your eyesight. Near the retina’s center is the macula, which serves central vision. It also contains the largest concentration of photoreceptors in the eye. It’s responsible for bringing detail and color to our sight. Because the macula demands so much oxygen to perform, oxidative stress and inflammation can severely impact eye and brain performance. It can cause a decrease in processing speed, contrast sensitivity and difficulty adjusting to low-light situations.

The body is aware of this, so it places three powerful carotenoids – Lutein, Meso-Zeaxanthin and Zeaxanthin – in the macula. Collectively, these carotenoids are called “macular pigment.” Their robust antioxidant properties make them capable of protecting the macula against free radicals. 

Because the macular pigment is colored yellow, it absorbs potentially harmful blue light. This leads to improved visual performance, including sharper colors, better contrast sensitivity and enhanced night vision. Studies show these carotenoids can also potentially delay (or even halt) the progression of AMD.

Lutein, Meso-Zeaxanthin and Zeaxanthin are essential nutrients for the eye and brain. However, our bodies can’t make them on their own. The average person consumes only one to two milligrams of macular carotenoids daily. This is because modern farming conditions have caused the nutritional value of fruits and vegetables to decline.1 Numerous studies show that taking supplements with all three macular carotenoids provides far superior results than taking Lutein and Zeaxanthin. Evidence also points to these nutrients reducing the risk of developing Alzheimer’s disease and slowing its progression.

Carotenoids Aren’t Just for Eyes

Studies show that carotenoids accumulate in the parts of the brain that interact with the retina, which can offer improved cognitive function. These nutrients combat oxidative stress that has built up over time. Research shows oxidative stress is the root cause of Alzheimer’s Disease, and carotenoids could be beneficial in managing the condition.

In one study3, the Nutrition Research Centre Ireland and the University Hospital Waterford divided Alzheimer’s patients into two groups. One took a carotenoid formula of 10mg of Lutein, 10mg of Meso-Zeaxanthin and 2mg of Zeaxanthin. The second group received fish oil consisting of 450 mg of DHA and the carotenoid formulation. A third (control) group of patients without Alzheimer’s Disease took only the carotenoid formula.

After a year and a half of supplementation, those who took the carotenoid formulation and the fish oil experienced improved cognitive function. The results are based on a series of independently performed tests, including functional benefits in memory, sight and mood.

Professor John Nolan, Ph.D., who led the study, explains: “Our previous work confirmed that Lutein, Meso-Zeaxanthin and Zeaxanthin are found in the eye and that enrichment of these essential nutrients with nutritional supplements can improve visual function. However, their high concentration in the healthy human brain also suggests a role for these nutrients in cognition.”

Based on overwhelming scientific evidence, it’s clear that we need sufficient amounts of Lutein, Meso-Zeaxanthin, and Zeaxanthin for optimal visual and cognitive health and performance. Thankfully, supplementation can help us reach the levels we need to realize all the benefits.  

References

  1. Johnson, E. J., Maras, J. E., Rasmussen, H. M., & Tucker, K. L. (2010). Intake of lutein and zeaxanthin differ with age, sex, and ethnicity. Journal of the American Dietetic Association, 110(9), 1357–1362. https://doi.org/10.1016/j.jada.2010.06.009
  2. Li, B., Ahmed, F., & Bernstein, P. S. (2010). Studies on the singlet oxygen scavenging mechanism of human macular pigment. Archives of biochemistry and biophysics, 504(1), 56–60. https://doi.org/10.1016/j.abb.2010.07.024
  3. Nolan, J. M., Mulcahy, R., Power, R., Moran, R., & Howard, A. N. (2018). Nutritional Intervention to Prevent Alzheimer’s Disease: Potential Benefits of Xanthophyll Carotenoids and Omega-3 Fatty Acids Combined. Journal of Alzheimer’s disease : JAD, 64(2), 367–378. https://doi.org/10.3233/JAD-180160
bioavailability
If your supplement has high bioavailability, then you're getting what you paid for.

MacuHealth

Written by MacuHealth
Reviewed by Jim Stringham, Ph.D.

The nutrients included in high-quality supplements offer plenty of health benefits for the human body and fill the nutritional gaps missing from the modern diet. But not all of them are created equal.

“We confirm that a number of commercially available carotenoid food supplements do not achieve their label claim,” explained Dr. David Phelan, Professor John Nolan and Dr. Alfonso Prado-Cabrero in their study on supplements in the journal Nutrients.1

A nutritional supplement’s effectiveness depends on absorption inside the body. But if it offers little to no bioavailability or your body has a difficult time absorbing its nutrients, then it’s not doing you any good.

What is bioavailability, and why is it so important? Bioavailability is effectively absorption – the fraction of active ingredients absorbed into the body’s circulation. It’s dependent on many factors. Knowing if a supplement has high bioavailability is crucial for a nutrient to be effective. Bioavailability also ensures that consumers are getting what they’re paying for. We’ll look at how bioavailability is measured and how supplements retain their potency.

How Does Bioavailability Work?

We absorb the ingredients we ingest in different ways. Some nutrients, such as carbohydrates and proteins, are easily processed into our bloodstream. But vitamins, minerals, antioxidants and other nutrients are more complicated, making it more difficult for our bodies to break them down and absorb them.

For example, a medication injected directly into the bloodstream should have 100 percent bioavailability. But an orally taken drug or supplement must pass through several barriers inside your body, such as your intestinal wall and liver. Some nutrients, such as Vitamin C, are water-soluble, meaning they’re absorbed when taken with water. Other nutrients, such as Vitamin E or carotenoids, are lipid-soluble, meaning that a small amount of fat is necessary for their transport across the intestinal wall into the bloodstream.

With orally ingested nutritional supplements, the fraction received by the body is usually measured with a blood draw. It won’t give you the exact fraction absorbed (higher is better), allowing for comparison among supplements and significant differences between them.

What Can Alter Bioavailability?

Though a supplement’s label may claim a certain amount of an active ingredient, the truth is that due to external factors, low-quality formulations and cost-saving techniques, it might be significantly lower. Factors that can alter the bioavailability of nutrients in supplements include the molecular structure of the active ingredients, the encapsulation process and your body’s own response.

Supplement's Molecular Structure and Formulation

The molecular structure and formulation of ingredients matter. For example, fish oil has re-esterified triglyceride and ethyl ester forms. While the latter is significantly cheaper, it’s much harder to absorb because of its synthetic form. The body recognizes re-esterified triglyceride fish oils, allowing them to be more easily absorbed.

Supplement's Encapsulation Method

Supplements are encapsulated in many forms: powder, softgel, liquid, etc. Powder-filled capsules tend to have a higher chance of degrading and losing bioavailability due to their clear interlock, making them more susceptible to light and oxidation. On the flipside, oil-filled softgels have airtight closing with more protection from heat, light, and oxygen – factors that can significantly degrade nutrients.

Body's Metabolism and Condition

Lastly, your body’s metabolism can affect how you absorb medications and supplements. Our natural digestive enzymes, like stomach acid, or certain intestinal disorders involving inflammation, can impair the passage of these essential substances into the bloodstream. As we grow older, our stomach produces less acid, which compromises our ability to absorb nutrients.

What to Look for in a Supplement

One thing a patient can do is check the label of their supplement. The manufacturer may recommend taking one with a meal because certain nutrients are fat-soluble, meaning they’re better absorbed with food. Taking a formulation with breakfast or dinner ensures the body receives all the active ingredients in a supplement.

Another thing to look for on the label is if the supplement is in tablet or capsule form. Most capsules contain oil-based formulations that are more stable and less likely to degrade than a tablet. Lastly, good nutritional supplements usually have peer-reviewed science behind their formulations. In their study, Dr. Phelan, Professor Nolan and Dr. Prado-Cabrero stated they believe that “clinicians and consumers should select…products which have appropriate scientific evidence confirming product stability and efficacy.” 

Eye supplements like MacuHealth feature Micro-MicelleTM Technology, which enhances the stability and bioavailability of the three carotenoids found in its patented formulation. In a recent clinical study, its formula provided the highest bioavailability with significantly higher serum and retinal response compared to a standard macular carotenoid supplement.2

Supplement Certified, an independent certification team based at the Nutrition Research Centre Ireland (NRCI) within the Waterford Institute of Technology, provides a rigorous analysis of supplements to ensure that their active ingredients retain their potency and stability throughout their shelf-life. MacuHealth is honored to carry its seal on all its products.

References

  1. Phelan, D., Prado-Cabrero, A., & Nolan, J. M. (2017). Stability of Commercially Available Macular Carotenoid Supplements in Oil and Powder Formulations. Nutrients, 9(10), 1133. https://doi.org/10.3390/nu9101133
  2. Green-Gomez, M., Prado-Cabrero, A., Moran, R., Power, T., Gómez-Mascaraque, L. G., Stack, J., & Nolan, J. M. (2020). The Impact of Formulation on Lutein, Zeaxanthin, and meso-Zeaxanthin Bioavailability: A Randomised Double-Blind Placebo-Controlled Study. Antioxidants (Basel, Switzerland), 9(8), 767. https://doi.org/10.3390/antiox9080767
macular degeneration symptoms
Are you experiencing any macular degeneration symptoms?

MacuHealth

Written by MacuHealth
Reviewed by Jim Stringham, Ph.D.

Those with macular degeneration symptoms are probably unable to identify when their vision started to change. Eyesight declines gradually, so it’s not uncommon for those with the disease to keep running errands, watching television or continuing work on various projects. But suddenly, colors become darker. Seeing directly ahead becomes a struggle. Vision starts to erode. And when the diagnosis finally becomes real, it can be a devastating and depressing blow.

The struggle to stay independent is why so many stories of age-related macular degeneration (AMD) remain untold. The condition flies under the radar of those most prone to it, but with a diagnosis of AMD comes the risk of losing your driver’s license, a diminished social life, and, in later stages of the disease, the inability to recognize the faces of loved ones.

Over 11 million people in the United States are affected by some form of AMD, with those over the age of 50 being the most vulnerable. According to the National Eye Institute, that number will likely double in 30 years. Exciting new research has given AMD sufferers some hope in battling this degenerative disease. Unfortunately, however, there is still no cure.

Understanding how AMD works and when it starts are keys to slowing or stopping its progression. We’ll take a closer look at macular degeneration symptoms, some treatments on the horizon and how those diagnosed with it can effectively manage their symptoms.

What are the Causes of AMD?

In finding a cure for AMD, the field of genetics looks particularly promising. According to WebMD, researchers have discovered at least 20 genes connected to AMD. But our family histories also put us at risk of developing the disease. If a member of your family has macular degeneration symptoms, your chances of getting the disease increases.

Family History, Gender, Race and Lifestyle Habits

Gender and race are other factors that increase the risk of AMD. Nearly two-thirds of those living with the condition are women, and a third of those afflicted are white. Almost a third of those 75 and older have AMD, and your chances of experiencing macular degeneration symptoms go up after you turn 50. Other factors that increase your AMD risk include smoking, obesity, high blood pressure and heart disease.

What is the Difference Between Dry and Wet Macular Degeneration?

Dry Macular Degeneration

There are two stages of AMD. The first kind is dry macular degeneration. The macula, the part of our retina that provides clear vision to our direct line of sight, begins to thin out and deteriorate as we grow older. Those suffering from dry macular degeneration symptoms may not lose their vision entirely. The disorder can develop in one or both eyes and worsen over time.

Wet Macular Degeneration

Dry macular degeneration can progress to the wet stage. Wet macular degeneration symptoms occur when new blood vessels grow underneath and into the macula. These irregular developments may leak fluid or blood, which blocks light from reaching the retina and harms its structure. Additionally, symptoms can occur when fluid builds up between the retina and a thin cell layer called the retinal pigment epithelium, causing distorted vision.

Macular Degeneration Symptoms

It can be difficult for people to know when macular degeneration symptoms begin. Sometimes, one’s vision declines slowly, with a slight change in color or a dark spot in the center of your field of view. Other times, straight lines can appear wavy. Regular visits to your eye care professional can help detect the disease early. Some other signs of AMD to look out for are:

  • A blurred or blind spot in the center of your vision
  • Difficulty adjusting your eyes in low-lit areas
  • Printed words that are fuzzy and difficult to read
  • Difficulty visually recognizing faces
  • Reduced ability to distinguish objects from their background

Can Macular Degeneration Symptoms Be Managed or Treated?

For anyone s­­truggling with macular degeneration symptoms, there is some hope. While there currently isn’t a cure for AMD, there are treatments that can help regulate its symptoms. The most important thing you can do is to see an optometrist regularly and get tested for AMD. There are also laser therapies or invasive drugs injected into the eye, both of which can halt the growth of abnormal blood vessels that can leak fluid into the retina. Some personal changes include quitting smoking and eating a balanced diet.

Supplements are a non-invasive, natural treatment shown to help AMD patients by replenishing macular pigment levels in the eye. With continuous supplementation, patients can dramatically reduce the risk of progression and improve their visual performance. MacuHealth, which includes all three carotenoids that make up the macular pigment, has been scientifically proven to protect the eye from damage, rebuild macular pigment and delay macular degeneration symptoms.

MacuHealth

macular degeneration progression timeline
Help determine where you stand visually with this macular degeneration progression timeline.

Written by MacuHealth
Reviewed by Jim Stringham, Ph.D.

According to the CDC, the prevalence of age-related macular degeneration (AMD) increases with age from 2% among people aged 40 to 44 to 46.6% among people aged at or greater than age 85. Data such as this can be scary, but there is a lot that you can do to reduce the risk of developing AMD and potentially slow its progression. While macular degeneration doesn’t always transition to vision loss, it can affect everyday tasks like reading, watching TV, and even recognizing the face of a loved one.

A macular degeneration diagnosis can be overwhelming, and many people want to know: how fast does macular degeneration progress? That’s why we’ve put together this macular degeneration progression timeline to help people categorize where they stand, what to expect in the future, and what they can do about it.

In this article, we’ll take an in-depth look at each of the stages of macular degeneration, discuss what to expect, and answer common questions. Read on for more information.

What Is Macular Degeneration?

Age-related macular degeneration is a progressive, neurodegenerative disease with an average age beginning around roughly 65 years old. At age 70, around 10 percent of individuals in the United States have an AMD diagnosis. It impacts central vision, with symptoms ranging from blurred or distorted eyesight to light sensitivity and difficulty seeing in low-light situations (e.g., driving at night). There are two main types of AMD: dry macular generation and wet macular degeneration. Before we delve into the macular degeneration progression timeline, let’s look at each in more detail.

What is Dry Macular Degeneration?

Dry AMD is the most common type of macular degeneration. This stage accounts for 80% to 90% of all cases. Healthcare professionals can spot the symptoms of dry macular degeneration as a progressive collection of yellowish spots or deposits called drusen that form under the retina.

In the case of people with dry macular degeneration, the biochemical pathways in the retina become dysfunctional, which leads to the buildup of the drusen in the retina. The buildup of drusen in the eye and biochemical pathways gives rise to excessive oxidative stress and inflammation. This can lead to irreversible damage to the retina’s light-sensing cells, which ushers in the aforementioned visual issues.

Patients suffering from dry macular degeneration experience central vision distortion and loss of vision over time. The dry macular degeneration progression timeline can be categorized into three stages, and it typically takes approximately five to ten years to reach the final stages.

The probability for developing dry AMD is determined primarily by genetics and lifestyle factors, like diet and exercise. The risk factors of dry macular degeneration include the following:

  • Age – It is common for symptoms of dry macular degeneration to appear in patients over 60 years old. 
  • Family history – Genetics can play a part in dry macular degeneration as it has a hereditary component. There are specific genes that are linked with this condition. Additionally, dry macular degeneration is more common in people of Caucasian descent. 
  • Obesity – Obesity can increase the chances of dry macular degeneration and the early stages of the condition and can lead to more advanced AMD cases.
  • Cardiovascular diseases – Heart or blood ailments can also cause patients to increase their chances of developing dry macular degeneration.
  • Smoking – Tobacco products can significantly increase the risk of developing dry macular degeneration.
  • Exercise – Regular, vigorous exercise is found to reduce the risk of AMD significantly. Sedentary behavior, therefore, is an important risk factor.

Dry macular degeneration can also lead to wet macular degeneration, the more severe form of the disease (more on this in the next section).

What is Wet Macular Degeneration?

Wet AMD, or late-stage AMD, is characterized by a more severe disease process involving leakage of blood into the retina and the growth of abnormal blood vessels. This ultimately results in the destruction of the light-sensitive retina and central visual blindness. This stage of AMD is relatively rare compared to dry AMD. Out of all macular degeneration conditions, wet macular degeneration accounts for approximately 20% of known cases. However, it is common for wet AMD to arise out of dry AMD.

Wet AMD often results in severe sight impairment or loss, which may happen rapidly. But exactly how quickly does wet macular degeneration progress? Although there is some variability, the wet macular degeneration timeline can take several months to progress from when symptoms appear to significant degeneration. In some cases, when left untreated, wet AMD can take mere days to advance to late-stage disease.

The factors that can increase the risk of wet macular degeneration are the same as dry macular degeneration. However, wet macular degeneration conditions can develop in a number of ways compared to dry macular degeneration. The different development causes are:

  • Vision loss caused by the irregular flow of blood vessel growth can cause leakages of blood and fluid from under the retina.
  • Vision loss caused by the buildup of fluid in the back of the eye. Fluid leaks build up in the back of the eye, resulting in the distortion or loss of vision.

What to Expect During the Macular Degeneration Progression Timeline

If you or a loved one has recently been diagnosed with macular degeneration, you may be wondering how quickly does macular degeneration progress and what to expect during each stage. As mentioned earlier, the dry macular degeneration timeline can take an average of five to ten years. But if you have the wet form of the disease, your timeline might be shorter. 

Below are some common symptoms that affect patients diagnosed with macular degeneration:

  • Visual distortions such as straight lines looking bent or crooked.
  • Reduced central vision out of a single or both eyes.
  • Need for brighter lights when performing everyday activities, such as performing close-up work or reading.
  • Difficulty adapting to dark rooms or light levels, including movie theaters or dimly lit restaurants.
  • Increased blurriness and difficulty reading printed texts and words.
  • Difficulty recognizing people’s faces. 
  • Well-defined blurry spot or a blind spot that does not go away. 

These symptoms can occur throughout the three different stages of macular degeneration: early, intermediate and advanced. Each one of these stages has different effects on the patient’s vision. Let’s look at each stage of macular degeneration in more detail.

Early Stage Macular Degeneration

Early macular degeneration can also be considered pre-macular degeneration as there are minimal to no side effects, like vision loss or blurriness. Optometrists can discover this early stage of macular degeneration through a routine eye exam by checking the level of drusen building up in the retina. The buildup of drusen can happen long before symptoms appear, which is why it’s important to schedule regular eye exams.

Once an optometrist detects an early indication of drusen buildup, they will tell patients to come back for frequent eye exams to monitor their condition or check for any signs of macular degeneration progression. They may also recommend a change in diet or supplementation with key nutrients to help slow the progression of AMD. Even if the patient has no symptoms, it is crucial that they follow up with these appointments and follow all instructions.   

Intermediate Stage Macular Degeneration

The intermediate stage is when AMD patients often begin to experience symptoms, including vision loss, blurriness and requiring more light to perform daily activities. An intermediate-stage macular degeneration diagnosis is based on the number and size of drusen in the eye. During this stage, the level of drusen buildup starts to advance, resulting in an increased risk of progressing to the advanced stage and experiencing life-changing symptoms.

Diagnoses for the intermediate stage require the presence of multiple medium-sized drusen or at least one large drusen in one eye or both eyes of the patient. It also requires that the pigmentation of the retina changes to become “splotchy” and not uniform.

Advanced Stage Macular Degeneration (Wet AMD)

This is the final stage of macular degeneration. By this point, patients have probably experienced almost all of the symptoms of the condition, including vision loss, blurriness, blind spots and leaking of fluids.

As the disease progresses, patients can expect blind spots to occur that block the central part of their vision. The result is that patients can have difficulty reading, recognizing faces, telling time on a clock – pretty much anything that requires sharp central vision. Patients may still be able to use their peripheral vision (side vision), though they may be classified as legally blind.

Macular Degeneration FAQs

Living with macular degeneration can be frightening and stressful, and chances are you have questions. Let’s go over some of the most frequently asked questions regarding this common age-related eye condition.

Can you stop the progression of macular degeneration?

At the time of this article’s writing, there is AMD has no cure. However, there are ways to improve symptoms, including incorporating a healthy diet, regular exercise, quitting smoking, and taking supplements for macular degeneration.

Can macular degeneration cause blindness?

The short answer is yes, but not fully. Even the worst-case scenarios of advanced macular degeneration typically only lead to central vision loss, not complete blindness. But if you experience extensive vision loss, how long does it take to go blind from macular degeneration? It typically takes approximately 5-10 years to progress from early-stage macular degeneration to the advanced stages. In advanced stages, vision loss may be severe enough that patients may be legally considered blind and should not drive or use machinery.

What is high myopia macular degeneration?

High myopia macular degeneration can occur if you suffer from extreme myopia (i.e., short-sightedness). Because those with high myopia are at increased risk for AMD, most people with this condition want to know: how fast does high myopia macular degeneration progress? Because it’s still a form of macular degeneration, it takes approximately ten years to progress to advanced stages.

Minimize Your Risk of Macular Degeneration

It’s important to schedule regular eye examinations with an experienced optometrist to

minimize your risk of developing AMD and causing the disease to progress. In addition, it’s important to eat a healthy diet (including lots of fruits and vegetables), engage in regular exercise, refrain from smoking, and take high-quality carotenoid supplements from a trusted retailer.

MacuHealth’s scientifically formulated eye supplements are clinically proven to protect your vision as you age, thanks to their research-backed ingredients and ability to rebuild macular pigment. MacuHealth’s formulations contain all three carotenoids vital to maintaining eye health (Meso-Zeaxanthin, Lutein and Zeaxanthin). Shop our eye vitamins for macular degeneration today!

best eye supplement
Not even the best eye supplements can improve your visual acuity, but they can help boost your contrast sensitivity.

MacuHealth

Written by MacuHealth
Reviewed by Jim Stringham, Ph.D.

Reading letters off the wall of our eye care specialists’ office is the eye test we’re probably most familiar with. Doctors have used it to measure clarity of vision – or visual acuity – for over a century because it’s reliable in helping to determine refractive error (blurry vision) and legal blindness. It serves as a good metric to track and manage ocular disease. But over the last several decades, the field of optometry has changed, and there are now many other methods for specialists to determine the quality of your vision.

We’ll look at another test your eye care professional can utilize to determine the quality of your visual function – contrast sensitivity. We’ll also examine how this aspect of your eyesight can help you in the real world and how the best eye supplements can help improve it.

What Does Visual Acuity Measure?

As stated above, if you’ve looked at a wall chart of letters or symbols during an exam, your eye care specialist is trying to determine your visual acuity. It’s a quick and easy way for your doctor to determine if your vision has changed and help them discover if you need an eyeglass or contact lens prescription.

 

A fraction, such as 20/20, symbolizes your visual acuity result. For example, if you have 20/20 vision, you can clearly see an object of a given size 20 feet away. This number doesn’t mean you have perfect sight – it is considered “good” vision. Most people won’t even have 20/20 vision unless prescribed corrective lenses. Not even the best eye supplements can help improve your result. Visual acuity depends largely on the optics of the eye and often requires corrective lenses.

What Is Contrast Sensitivity?

Contrast sensitivity is the ability to detect subtle differences in shading and patterns. It effectively allows us to distinguish objects in our visual field. It’s an essential measure of visual function, especially in situations of low light, fog or glare, when the contrast between objects and their environment is reduced. Having good contrast sensitivity is vital for driving at night.

 

A contrast sensitivity test measures your ability to distinguish between finer and finer increments of light versus dark. Often individuals can detect differences as low as 2 percent. In terms of “real-world” vision, a contrast sensitivity test captures significantly more information than a visual acuity test.

 

Your contrast sensitivity may not be up to par, even if you have 20/20 visual acuity. Interestingly, research shows that nutritional supplements containing the three macular carotenoids (Lutein, Zeaxanthin and Meso-Zeaxanthin) can boost contrast sensitivity.

How Is Contrast Sensitivity Measured?

There are two general contrast sensitivity tests. The most widely used is the Pelli-Robson test, which consists of different capital letters organized in horizontal lines. The contrast decreases with each line. You read the letters down the chart to determine the level you can see. A better contrast sensitivity test is a sinewave grating test. It consists of several dark and light parallel bars to provide a more acute way to see how your eyes detect contrast.

As you may know, contrast sensitivity testing isn’t part of a typical eye exam. If you feel something is affecting your visual contrast, ask your eye care professional to perform a Pelli-Robson or sinewave grating test.

What Can the Best Eye Supplements Do to Improve Contrast Sensitivity?

A contrast sensitivity test will allow your eye care professional to determine if your visual performance is reasonably good. It can also potentially detect eye disease much sooner – allowing them to recommend a treatment plan based on your needs.

In many cases, your doctor may recommend supplements to rebuild macular pigment and optimize the use of light at the retina in a way that eyeglasses and contact lenses cannot provide. MacuHealth’s patented formula is one of the best eye supplements available, and many doctors recommend it because it is scientifically proven to improve contrast sensitivity and visual performance. To learn more, click here to shop for MacuHealth now.

peer reviewed journal
It takes a lot of research to have a study in a peer-reviewed journal.

MacuHealth

Written by MacuHealth
Reviewed by Jim Stringham, Ph.D.

Nutritional supplements are notoriously unregulated. This allows companies to make false claims about their products and put inactive ingredients in their formulations. As bad as this may sound, it has happened.

So, who can you trust?  The most effective way to evaluate any product claims is to examine the science (if any) conducted on it.  Some companies may conduct in-house scientific testing and often advertise their “findings” on their website or social media. Yet, the most trusted and respected form of science is called peer-reviewed.

But what does being peer-reviewed mean to patients? We’ll define what the term means and review what research must undergo to achieve this status.

What Does Peer-Reviewed Mean?

In a nutshell, a peer-reviewed journal is what the name suggests: a publication featuring scientific investigations analyzed by at least two other independent researchers (peers) in the same area of study. More specifically, the peer review process is a form of quality control intended to weed out poorly researched work. This helps to maintain a journal’s integrity.

But to fully understand what becoming “peer-reviewed” is, it’s essential to understand the distinction between a piece found in a widely published periodical or on social media and a peer-reviewed journal.

Before a newspaper or a magazine publishes an article, an editor checks it for readability by a large audience. Then, a fact-checker makes sure any facts the author used have not changed. Usually, the author, editor or fact-checker is not an expert in a particular field.

When a scholar sends their research for publication to a peer-reviewed journal, the editor ensures that it’s written for an audience of researchers. This means it’ll contain terms typically understood by experts. But instead of sending it to one person for a fact-check, the journal’s editor sends these findings to peers as an extra step in the publication process.

The Process of Becoming Peer-Reviewed

The method of being in a peer-reviewed journal can be complicated and lengthy. According to the American Psychological Association, here are the four steps of the journey:

  1. A scholar submits their research paper to a journal. The peer-reviewed journal’s editor determines if the manuscript is free from flaws or conflicts of interest. Afterward, it selects qualified individuals in the author’s field of study to offer a fair review.
  2. Review Research and Statistics.The editor and the selected peers review the entire paper, including any tables or figures attached. This ensures the information follows the publication’s guidelines and is well-organized, coherent, clearly defined and relevant. Often, the process is double-blind, meaning the author and reviewers are unknown to avoid bias.
  3. It can take several weeks for a peer-reviewed journal to decide to publish a paper. Most get sent back to the author with suggestions for revision. Feedback can include reorganizing the research structure or conducting additional experiments. The peers who reviewed the original document will usually view the revised manuscript.
  4. If the revisions are approved, the editor will schedule the paper for publication. If the author receives a rejection and believes a point was overlooked or misunderstood, they can appeal the decision. The time from submission to publication can be nearly a year.

The Benefits of Being in a Peer-Reviewed Jourmal

MacuHealth embraces science, and completing the peer-review process is a significant test of scientific integrity. There are over 40 peer-reviewed publications that support the effectiveness, bioavailability, and safety of MacuHealth’s formulations. Despite the length of time it takes to be peer-reviewed, it’s vital for the protection and trust of its customers.

When researchers evaluating MacuHealth publish their studies in a peer-reviewed journal, it gives eye care professionals and patients confidence to trust its claims and realize the supplement’s health benefits. Our willingness to undergo this process sets MacuHealth apart from the competition.

MacuHealth

macular pigment
Macular pigment can help with eye strain caused by use of computers and smartphones.

Written by MacuHealth
Reviewed by Jim Stringham, Ph.D.

Do carrots boost your eyesight? Scientific American published an article that puts an end to the debate. 

What was their conclusion? Carrots are rich in the carotenoid beta-carotene; the body converts beta-carotene into vitamin A, which can improve your vision under certain conditions, such as a vitamin A deficiency. And while vitamin A is vital to prevent blindness and maintain the health of the cornea (the clear front of the eye), there isn’t a definite answer on how many carrots it would take to improve one’s vision.

But other vegetables are shown to boost eyesight because of the nutrients they contain. Broccoli, corn, squash and dark green leafy vegetables like spinach and kale are rich in the carotenoids Lutein and Zeaxanthin. These are two of the three carotenoids deposited in the central retina (called the “macula”), where they accumulate to form the macular pigment. These nutrients have a yellow-orange coloration that enables it to filter potentially harmful blue light.

They also protect against oxidative stress and inflammation and enhance visual performance. The macula is the part of the eye responsible for central vision, which most people consider to be the most vital aspect of your sight. It allows you to see fine detail, recognize faces, and read this text! Indeed, the central retina brings color and detail to everything you see.

How do you increase macular pigment? Is eating vegetables enough to replenish this small but vital substance in the eye? We’ll take a closer look at how to put more carotenoids in our diet.

What Do Lutein and Zeaxanthin Do?

As noted above, Lutein and Zeaxanthin are dietary carotenoids that filter damaging high-energy blue wavelength light from the visible-light spectrum by as much as 90 percent. They’re also antioxidants that protect against the damage caused by free radicals produced through normal body processes. Environmental sources of free radicals include cigarette smoke, air pollutants, radiation, certain drugs and environmental toxins.

How do you increase macular pigment with these carotenoids? In a 1994 Journal of American Medical Association report, Dr. Johanna M. Seddon and her associates at Harvard University found that six mg per day of lutein over the lifespan leads to a 43 percent lower risk for AMD.

 

“When we compared the amount of macular pigment, which is comprised of Lutein and Zeaxanthin, present in the eyes of people with age-related macular degeneration to people without the disease, those with the lowest levels of carotenoid accumulation in the outer retina were significantly more likely to suffer from age-related macular degeneration than those with higher pigment levels,” said Dr. Landrum. “The difference in risk between those having the highest and lowest levels was 75 percent.”

But Isn't There A Third Macular Carotenoid?

Meso-Zeaxanthin, the most potent antioxidant of the three macular carotenoids, is only found in the center of the macula, where vision is the sharpest. How do you increase macular pigment with Meso-Zeaxanthin? It’s obtained by an enzyme that converts ingested Lutein inside the retina. Most AMD patients have 30 percent less Meso-Zeaxanthin in their macula and are unable to convert Lutein into Meso-Zeaxanthin. To be sure you’ve got enough of all three macular carotenoids, a supplement containing all three is optimal.

Who Benefits from Enriching Macular Pigment?

Nearly everyone will benefit from enriching and maximizing macular pigment throughout their lifetime. Our diets are generally lower in nutrients, and modern technology has dictated that we’re exposed to more blue light. Although everyone can benefit from enriching macular pigment, the following people will benefit the greatest:

Children and Young Adults

This group is more susceptible to damage from high-energy blue light emitting from our computers, tablets, smartphones and energy-efficient fluorescent lights. Their lives revolve around these devices, and they’re holding them closer to their faces, which increases the intensity of blue light.

Pre- and Post-Cataract Patients

Post-cataract patients have had their crystalline lens removed and replaced with an intra-ocular lens. Once the lens of the eye is removed, the yellowing of this lens, which is also a natural blue light filter, is also removed. When the cataract is removed, the lens returns to its clear, child-like form. This makes the macula more susceptible to blue light and the photooxidation that accompanies it.

Age-Related Macular Degeneration

Patients diagnosed with age-related macular degeneration (AMD), a disease with no cure, have a significantly increased risk of blindness as the disease progresses. Often, the disease starts in one eye and can affect the other eye at some later time. The increased macular pigment can slow the progression of AMD, help save the vision in the diseased eye and potentially delay the onset of the disease in the other eye.

Furthermore, family members of those diagnosed with AMD are at higher risk of developing the disease. Family history and genetics are the greatest risk factors for developing AMD. If one of your parents, grandparents or a sibling has the disease, your risk of disease onset increases. Building up macular pigment earlier in life should be strongly considered.

Those with Visually Demanding Careers

People with occupations that have critical vision requirements can benefit significantly from increasing their macular pigment density. Several studies have shown that the enrichment of macular pigment optimizes visual performance for athletes, the military and the police.

How Do You Increase Macular Pigment, and Why Is It Vital for Our Vision?

We can’t take macular pigment for granted. It is no accident that the ingredients that make up this protective layer in the eye accumulate in the center of the retina, where vision is the sharpest (particularly color vision), and oxidative stress is abundant.

These ingredients limit injury at the retina by absorbing the amount of short wavelength (blue) visible light incident upon the photoreceptors. But humans cannot synthesize macular carotenoids – we need to obtain them from diet or supplementation. Our diets have fewer of these critical nutrients due to a significant increase in processed foods. Even a healthy diet often does not provide enough of these nutrients to protect our vision from oxidation over our lifetime.

Thankfully, there is a supplement that contains all three macular carotenoids in a dose that has been shown to significantly increase macular pigment: MacuHealth. MacuHealth is scientifically proven to protect the eye from damage, rebuild macular pigment and manage the symptoms of AMD.

Follow Us On:
Instagram Facebook Linkedin
© MacuHealth 2024. All Rights Reserved.
FDA Disclaimer

These statements have not been evaluated by the Food and Drug Administration. Products are not intended to diagnose, treat, cure or prevent any disease. 

Products

Resources

EYE CARE PROFESSIONALS

ABOUT US